Effective dose of topiramate in pediatric migraine prophylaxis
نویسندگان
چکیده
منابع مشابه
Topiramate for migraine prophylaxis.
Topiramate is a neurmodulatory compound with neuron stabilizing properties and is approved for the preventive treatment of migraine in several countries [5]. Several small and large trials have reported good efficacy and safety of topiramate in migraine prophylaxis in adults [6]. The present study was done to study the role of topiramate in migraine prophylaxis in children who either failed to ...
متن کاملProphylaxis of Childhood Migraine: Topiramate Versus Propranolol
OBJECTIVE Headache is a common disabling neurological disorder and migraine comprises more than half the causes of recurrent headaches in children. Despite extended prevalence of this type of headache there is lack of evidence about best drug treatment for migraine. So we aimed to compare the therapeutic effects of these drugs on childhood migraine. MATERIALS & METHODS In the current study, a...
متن کاملFactors Associated with Favorable Outcome of Topiramate Migraine Prophylaxis in Pediatric Patients
BACKGROUND AND PURPOSE There are few studies that have investigated predictive factors related to migraine prophylaxis of which produced inconsistent results. The aim of this study was to identify factors that can predict the treatment response to topiramate prophylaxis in pediatric patients with migraine. METHODS One hundred and thirteen patients who were older than 7 years and received topi...
متن کاملTopiramate as Migraine Prophylaxis in Pediatric Patients: An Integrated Summary of Randomized Controlled Trials
Background: An integrated analysis of five randomized, placebo-controlled studies in migraine prophylaxis was conducted to assess topiramate’s efficacy and safety in pediatric patients. Methods: Study 1, a pivotal study (50-, 100 mg/day; aged 12-17 years), Study 2 (flexibly-dosed 2-3 mg/kg/day; aged 6-15 years), and Studies 3, 4 and 5 [50-, 100-, 200 mg/day; aged ≥ 12 years)]. Results: Percent ...
متن کاملEfficacy of Topiramate in Migraine Prophylaxis: a Randomized Controlled Study*
Topiramate has been under investigation for the past several years as a prophylactic agent for migraine and other headache disorders. Studies to date have shown it to be safe and effective. As with other antiepileptic drugs, its exact mechanisms of action are not yet known, or at least, the mechanisms that are important in its efficacy in migraine are not yet defined. Topiramate acts on several...
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ژورنال
عنوان ژورنال: Journal of Pediatric Neurosciences
سال: 2012
ISSN: 1817-1745
DOI: 10.4103/1817-1745.106470